A. Ball, K. Khatri, J. Glesner, L. D. Vailes, S. Wünschmann, S. A. Gabel, G. A. Mueller, J. Zhang, R. S. Peebles, M. D. Chapman, S. A. Smith, M. Chruszcz, A. Pomés. Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2. Journal of Allergy and Clinical Immunology. 2024 (154:2). https://doi.org/10.1016/j.jaci.2024.04.017
R.W.R. Crevel, K. Verhoeckx, K.L. Bøgh, N. Buck, A. Chentouf, S. Flanagan f, M. Galano, J.A. Garthoff, S. Hazebrouck, R. Yarham, G. Borja, G. Houben. Allergenicity assessment of new or modified protein-containing food sources and ingredients. Food and Chemical Toxicology. 2024 July (189). https://doi.org/10.1016/j.fct.2024.114766
E. Zoratti, R. Wood, A. Pomés, R. Da Silva Antunes, M. C. Altman, B. Benson, L. M. Wheatley, K. Cho, A. Calatroni, F. F. Little, J. Pongracic, M. Makhija, G. K. Khurana Hershey, M. G. Sherenian, K. Rivera-Spoljaric, J. R. Stokes, M. A. Gill, R. S. Gruchalla, J. Chambliss, A. H. Liu, M. Kattan, P. J. Busse, L. B. Bacharier, W. Sheehan, H. Kim, J. Glesner, P. J. Gergen, A. Togias, J. L. Baucom, C. M. Visness, A. Sette, W. W. Busse, D. J. Jackson. A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy. Journal of Allergy and Clinical Immunology. 2024. https://doi.org/10.1016/j.jaci.2024.04.022
A. Pomés, S. A. Smith, M. Chruszcz, G. A. Mueller, N. F. Brackett, M. D. Chapman. Precision engineering for localization, validation, and modification of allergenic epitopes. Journal of Allergy and Clinical Immunology. 2024 (153:3). https://doi.org/10.1016/j.jaci.2023.12.017
Grant TL, Wood RA, Chapman MD. Indoor Environmental Exposures and Their Relationship to Allergic Diseases. J Allergy Clin Immunol Pract. 2023 Oct;11(10):2963-2970. doi:10.1016/j.jaip.2023.08.034
Meredith RT, Yarham RAR, Mills H, Oliver, MA. Whole blood cytokine release assays reveal disparity between capillary blood sampling methods. Clinical Biochemistry. 2023 Sep (120). doi.org/10.1016/j.clinbiochem.2023.110648
Smith BRE, Reid Black K, Bermingham M, Agah S, Glesner J, Versteeg SA, van Ree R, Pena-Amelunxen G, Aglas L, Smith SA, Pomés A and Chapman MD. Unique allergen specific human IgE monoclonal antibodies derived from patients with allergic disease. Front. Allergy 4:1270326. doi: 10.3389/falgy.2023.1270326
Stone CA Jr, Hemler JA, Filep S, Braden K, Pomés A, Chapman MD, Smith SA. Quantification of peanut allergens across recalled and nonrecalled lots of diagnostic peanut extracts. J Allergy Clin Immunol Pract. 2023 Nov;11(11):3547-3549.e1. doi: 10.1016/j.jaip.2023.07.015
Meredith R.T, Bermingham M.D, Bentley K, Agah S, Aboagye-Odei A, Yarham R.A.R, Mills H, Shaikh M, Hoye N, Stanton R.J, Chadwick D.R, Oliver M.A. Differential cellular and humoral immune responses in immunocompromised individuals following multiple SARS-CoV-2 vaccinations. Frontiers in Cellular and Infection Microbiology. 2023 Jun 23 (13). doi.org/10.3389/fcimb.2023.1207313
Pena-Castellanos G, Smith B.R.E, Pomés A, Smith S.A, Stigler M.A, Widauer H.L, Versteeg S.A, van Ree R, Chapman M.D, Aglas L. Biological activity of human IgE monoclonal antibodies targeting Der p 2, Fel d 1, Ara h 2 in basophil mediator release assays. Frontiers in Immunology. 2023 May 09 (14). doi.org/10.3389/fimmu.2023.1155613
Smith, S.A., Chruszcz, M., Chapman, M.D. et al. Human Monoclonal IgE Antibodies—a Major Milestone in Allergy. Curr Allergy Asthma Rep 23, 53–65 (2023). https://doi.org/10.1007/s11882-022-01055-w
LaHood NA, Min J, Keswani T, Richardson CM, Amoako K, Zhou J, Marini-Rapoport O, Bernard H, Hazebrouck S, Shreffler WG, Love JC, Pomés A, Pedersen LC, Mueller GA, Patil SU. Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy. J Clin Invest. 2023 Jan 17;133(2):e164501. doi: 10.1172/JCI164501
Filep SC, Reid Black K, Smith BRE, Block DS, Kuklinska-Pijanka A, Bermingham M, Oliver MA, Thorpe CM, Schuhmacher ZP, Agah S, Wuenschmann S, Chapman MD. Simultaneous quantification of specific food allergen proteins using a fluorescent multiplex array. Food Chem. 2022 Sep 30;389:132986. doi: 10.1016/j.foodchem.2022.132986. Epub 2022 Apr 18. PMID: 35569245.
Urrutia-Pereira M, Chong-Neto HJ, Annesi Maesano I, Ansotegui IJ, Caraballo L, Cecchi L, Galán C, López JF, Aguttes MM, Peden D, Pomés A, Zakzuk J, Rosário Filho NA, D’Amato G. Environmental contributions to the interactions of COVID-19 and asthma: A secondary publication and update. World Allergy Organ J. 2022 Sep;15(9):100686. doi: 10.1016/j.waojou.2022.100686. Epub 2022 Aug 8. PMID: 35966894; PMCID: PMC9359502.
Oliver MA, Meredith RT, Smith BR, Bermingham MD, Brackett NF, Chapman MD. Longitudinal T cell responses against ancestral, delta, and omicron SARS-CoV-2 variants determined by rapid cytokine release assay in whole blood. Immunohorizons. 2022 Jun 24;6(6):398-407. doi: 10.4049/immunohorizons.2200044. PMID: 35750357.
Khatri K, Richardson CM, Glesner J, Kapingidza AB, Mueller GA, Zhang J, Dolamore C, Vailes LD, Wünschmann S, Peebles RS Jr, Chapman MD, Smith SA, Chruszcz M, Pomés A. Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo. PNAS Nexus. 2022 Jun 2;1(3):pgac054. doi: 10.1093/pnasnexus/pgac054. PMID: 35799831; PMCID: PMC9248284.
Brackett NF, Davis BW, Adli M, Pomés A, Chapman MD. Evolutionary biology and gene editing of cat allergen, Fel d 1. CRISPR J. 2022 Apr;5(2):213-223. doi: 10.1089/crispr.2021.0101. Epub 2022 Mar 28. PMID: 35343817.
Brackett NF, Pomés A, Chapman MD. New Frontiers: precise editing of allergen genes using CRISPR. Front Allergy. 2022 Jan 17;2:821107. doi: 10.3389/falgy.2021.821107. PMID: 35386981; PMCID: PMC8974684.
Filep S, Chapman MD. Doses of specific allergens in early introduction foods for prevention of food allergy. J Allergy Clin Immunol Pract. 2022 Jan;10(1):150-158.e3. doi: 10.1016/j.jaip.2021.02.051. Epub 2021 Mar 8. PMID: 33711495.
Abhyankar MM, Mann BJ, Sturek JM, Brovero S, Moreau GB, Sengar A, Richardson CM, Agah S, Pomés A, Kasson PM, Tomai MA, Fox CB, Petri WA Jr. Development of COVID-19 vaccine using a dual Toll-like receptor ligand liposome adjuvant. NPJ Vaccines. 2021 Nov 18;6(1):137. doi: 10.1038/s41541-021-00399-0. PMID: 34795290; PMCID: PMC8602664.
da Silva Antunes R, Sutherland A, Frazier A, Schulten V, Pomés A, Glesner J, Calatroni A, Altman MC, Wood RA, O’Connor GT, Pongracic JA, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Gill M, Liu AH, Zoratti E, Kattan M, Busse PJ, Bacharier LB, Teach SJ, Wheatley LM, Togias A, Busse WW, Jackson DJ, Sette A. Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children. Clin Transl Allergy. 2021 Oct 13;11(8):e12073. doi: 10.1002/clt2.12073. PMID: 34691392; PMCID: PMC8514843.
Platts-Mills TA, Hilger C, Jappe U, van Hage M, Gadermaier G, Spillner E, Lidholm J, Keshavarz B, Aalberse RC, van Ree R, Goodman RE, Pomés A. Carbohydrate epitopes currently recognized as targets for IgE antibodies. Allergy. 2021 Aug;76(8):2383-2394. doi: 10.1111/all.14802. PMID: 33655520; PMCID: PMC8489568.
Chruszcz M, Chew FT, Hoffmann-Sommergruber K, Hurlburt BK, Mueller GA, Pomés A, Rouvinen J, Villalba M, Wöhrl BM, Breiteneder H. Allergens and their associated small molecule ligands-their dual role in sensitization. Allergy. 2021 Aug;76(8):2367-2382. doi: 10.1111/all.14861. Epub 2021 May 2. PMID: 33866585; PMCID: PMC8286345.
Maciag MC, Sheehan WJ, Bartnikas LM, Lai PS, Petty CR, Filep S, Chapman MD, Phipatanakul W. Detection of food allergens in school and home environments of elementary students. J Allergy Clin Immunol Pract. 2021 Oct;9(10):3735-3743. doi: 10.1016/j.jaip.2021.06.014. Epub 2021 Jun 24. PMID: 34174494; PMCID: PMC8511097.
Pomés A, Schulten V, Glesner J, da Silva Antunes R, Sutherland A, Bacharier LB, Beigelman A, Busse P, Frazier A, Sette A. IgE and T cell reactivity to a comprehensive panel of cockroach allergens in relation to disease. Front Immunol. 2021 Feb 10;11:621700. doi: 10.3389/fimmu.2020.621700. PMID: 33643303; PMCID: PMC7902920.
Rosário Filho NA, Urrutia-Pereira M, D’Amato G, Cecchi L, Ansotegui IJ, Galán C, Pomés A, Murrieta-Aguttes M, Caraballo L, Rouadi P, Chong-Neto HJ, Peden DB. Air pollution and indoor settings. World Allergy Organ J. 2021 Jan 7;14(1):100499. doi: 10.1016/j.waojou.2020.100499. PMID: 33510831; PMCID: PMC7806792.
Hindley JP, Oliver MA, Thorpe C, Cullinane A, Wuenschmann S, Chapman MD. Bos d 11 in baked milk poses a risk for adverse reactions in milk-allergic patients. Clin Exp Allergy. 2021 Jan;51(1):132-140. doi: 10.1111/cea.13774. Epub 2020 Nov 15. PMID: 33141480.
Mueller GA, Glesner J, Daniel JL, Zhang J, Hyduke N, Richardson CM, DeRose EF, Chapman MD, Peebles RS Jr, A Smith S, Pomés A. Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2. J Immunol. 2020 Oct 15;205(8):1999-2007. doi: 10.4049/jimmunol.2000295. Epub 2020 Sep 9. PMID: 32907999; PMCID: PMC7541722.
Goodman RE, Chapman MD, Slater JE. The Allergen: sources, extracts, and molecules for diagnosis of allergic disease. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2506-2514. doi: 10.1016/j.jaip.2020.06.043. PMID: 32888526.
Pomés A, Mueller GA, Chruszcz M. Structural aspects of the allergen-antibody interaction. Front Immunol. 2020 in press.
Pomés A, Schulten V. Cross-reactivity in allergy: a double-edged sword. Allergy. 2020 Jan;75(1):9-11. PMCID: PMC6952562.
Caraballo L, Valenta R, Puerta L, Pomés A, Zakzuk J, Fernandez-Caldas E, Acevedo N, Sanchez-Borges M, Ansotegui I, Zhang L, van Hage M, Fernández E, Arruda L, Vrtala S, Curin M, Gronlund H, Karsonova A, Kilimajer J, Riabova K, Trifonova D, Karaulov A. The allergenic activity and clinical impact of individual IgE-antibody binding molecules from indoor allergen sources. World Allergy Organ J. 2020 Apr 29;13(5):100118. PMCID: PMC7195550.
Aalberse RC, Mueller GA, Derksen NIL, Aalberse JA, Edwards LL, Pomés A, Lidholm J, Rispens T, Briza P. Identification of the amino-terminal fragment of Ara h 1 as a major target of the IgE-binding activity in the basic peanut protein fraction. Clin Exp Allergy. 2020;50(3):401-405. PMCID: PMC7047623.
Pomés A, Schal C. Cockroach and Other Inhalant Insect Allergens. Chapter 15 in: Lockey RF, Ledford DK (eds): Allergens and Allergen Immunotherapy for Allergic Diseases, Subcutaneous, Sublingual and Oral, 6th edition. CRC Press/Taylor & Francis Group, New York, NY, 2020.
Breiteneder H, Goodman R, Chapman MD, Pomés A. Allergen Nomenclature. Chapter 3 In: Lockey RF, Ledford DK (eds): Allergens and Allergen Immunotherapy for Allergic Diseases, Subcutaneous, Sublingual and Oral, 6th edition. CRC Press/Taylor & Francis Group, New York, NY, 2020.
Glesner J, Kapingidza AB, Godzwon M, Offermann LR, Mueller GA, DeRose EF, Wright P, Richardson CM, Woodfolk JA, Vailes LD, Wünschmann S, London RE, Chapman MD, Ohlin M, Chruszcz M, Pomés A. A human IgE antibody binding site on Der p 2 for the design of a recombinant allergen for immunotherapy. J Immunol. 2019 In press. Cover of J. Immunol. PMCID: PMC6810898.
Chan SK, Pomés A, Hilger C, Davies JM, Mueller G, Kuehn A, Lopata AL, Gadermaier G, van Hage M, Raulf M, Goodman RE. Keeping allergen names clear and defined. Front Immunol. 2019;10:2600.
Pomés A, Glesner J, Calatroni A, Visness CM, Wood RA, O’Connor GT, Kattan M, Bacharier LB, Wheatley LM, Gern JE, Busse WW; National Institute of Allergy and Infectious Diseases–funded Inner-City Asthma Consortium. Cockroach allergen component analysis of children with or without asthma and rhinitis in an inner-city birth cohort. J Allergy Clin Immunol. 2019 Oct;144(4):935-944. PMCID: PMC7307589.
Birrueta G, Frazier A, Pomés A, Glesner J, Filep S, Schal C, Jeong KY, McMurtrey C, Vander Schans T, Hildebrand WH, Busse P, Beigelman A, Bacharier LB, Peters B, Sette A, Schulten V. Variability in German cockroach extract composition greatly impacts T cell potency in cockroach-allergic donors. Front Immunol. 2019 Feb 27;10:313. PMCID: PMC6413722.
Mueller GA, Min J, Foo ACY, Pomés A, Pedersen LC. Structural analysis of recent allergen-antibody complexes and future directions. Curr Allergy Asthma Rep. 2019;19(3):17. PMCID: PMC6688168.
Glesner J, Filep S, Vailes LD, Wünschmann S, Chapman MD, Birrueta G, Frazier A, Jeong KY, Schal C, Bacharier L, Beigelman A, Busse P, Schulten V, Sette A, Pomés A. Allergen content in German cockroach extracts and sensitization profiles to a new expanded set of cockroach allergens determine in vitro extract potency for IgE reactivity. J Allergy Clin Immunol. 2019 Apr;143(4):1474-1481. PMCID: PMC6395535.
Pomés A, Davies JM, Gadermaier G, Hilger C, Holzhauser T, Lidholm J, Lopata AL, Mueller GA, Nandy A, Radauer C, Chan SK, Jappe U, Kleine-Tebbe J, Thomas WR, Chapman MD, van Hage M, van Ree R, Vieths S, Raulf M, Goodman RE; WHO IUIS Allergen Nomenclature Sub-Committee. WHO/IUIS Allergen Nomenclature: Providing a common language. Mol Immunol. 2018;100:3-13. PMCID: PMC6019191.
Filep S, Block DS, Smith BRE, King EM, Commins S, Kulis M, Vickery BP, Chapman MD. Specific allergen profiles of peanut foods and diagnostic or therapeutic allergenic products. J Allergy Clin Immunol. 2018;141(2):626-631.
Hindley JP, Filep S, Block DS, King EM, Chapman MD. Dose of allergens in a peanut snack (Bamba) associated with prevention of peanut allergy. J Allergy Clin Immunol. 2018;141(2):780-782.
Sánchez-Borges M, Fernandez-Caldas E, Thomas WR, Chapman MD, Lee BW, Caraballo L, Acevedo N, Chew FT, Ansotegui IJ, Behrooz L, Phipatanakul W, Gerth van Wijk R, Pascal D, Rosario N, Ebisawa M, Geller M, Quirce S, Vrtala S, Valenta R, Ollert M, Canonica GW, Calderón MA, Barnes CS, Custovic A, Benjaponpitak S, Capriles-Hulett A. International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem. World Allergy Organ J. 2017;10(1):14. PMCID: PMC5394630.
Pomés A, Mueller GA, Randall TA, Chapman MD, Arruda LK. New insights into cockroach allergens. Curr Allergy Asthma Rep. 2017;17(4):25. PMCID: PMC5575827.
Glesner J, Vailes LD, Schlachter C, Mank N, Minor W, Osinski T, Chruszcz M, Chapman MD, Pomés A. Antigenic Determinants of Der p 1: Specificity and cross-reactivity associated with IgE antibody recognition. J Immunol. 2017;198(3):1334-1344. PMCID: PMC5263215.
Lawrence MG, Woodfolk JA, Schuyler AJ, Stillman LC, Chapman MD, Platts-Mills TA. Half-life of IgE in serum and skin: Consequences for anti-IgE therapy in patients with allergic disease. J Allergy Clin Immunol. 2017;139(2):422-428. PMCID: PMC5405770.
Ogburn RN, Randall TA, Xu Y, Roberts JH, Mebrahtu B, Karnuta JM, Rider SD, Kissling GE, London RE, Pomés A, Arlian L, Fitzgerald MC, Mueller GA. Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins? J Allergy Clin Immunol. 2017;139(3):1030-1032. PMCID: PMC5342938.
Muehling LM, Mai DT, Kwok WW, Heymann PW, Pomés A, Woodfolk JA. Circulating memory CD4+ T cells target conserved epitopes of rhinovirus capsid proteins and respond rapidly to experimental infection in humans. J Immunol. 2016;197(8):3214-3224. PMCID: PMC5101128.
Pomés A, Chapman MD, Wünschmann S. Indoor allergens and allergic respiratory disease. Curr Allergy Asthma Rep. 2016;16(6):43. PMCID: PMC4976688.
Woodfolk JA, Glesner J, Wright PW, Kepley CL, Li M, Himly M, Muehling LM, Gustchina A, Wlodawer A, Chapman MD, Pomés A. Antigenic determinants of the bilobal cockroach allergen Bla g 2. J Biol Chem. 2016;291(5):2288-301. PMCID: PMC4732212
Mueller GA, Randall TA, Glesner J, Pedersen LC, Perera L, Edwards LL, DeRose EF, Chapman MD, London RE, Pomés A. Serological, genomic and structural analyses of the major mite allergen Der p 23. Clin Exp Allergy. 2016;46(2):365-376. PMCID: PMC4732897.
Pomés A, Wünschmann S, Chapman MD. Allergens. In: Encyclopedia of Immunobiology, 1st ed. Ratcliffe, M.J.H. (Editor in Chief). 2016;Vol. 5, pp. 281–289. Oxford: Academic Press.
López-Matas MA, Iraola V, Moya R, Vailes LD, Pomés A, Boquete M, Fernández-Caldas E, Arlian LG, Chapman M, Carnés J. Cloning and characterization of tropomyosin from the mite Chortoglyphus arcuatus. Mol Immunol. 2015;68(2 Pt C):634-40.
Chapman MD, Wuenschmann S, King E, Pomés A. Erratum to: Technological Innovations for High-Throughput Approaches to In Vitro Allergy Diagnosis. Curr Allergy Asthma Rep. 2015;15(8):52. PMCID: PMC4832979.
Pomés A, Chruszcz M, Gustchina A, Minor W, Mueller GA, Pedersen LC, Wlodawer A, Chapman MD. 100 Years later: Celebrating the contributions of x-ray crystallography to allergy and clinical immunology.
J Allergy Clin Immunol. 2015;136(1):29-37. PMCID: PMC4502579.
Chapman MD, Wuenschmann S, King E, Pomés A. Technological Innovations for High-Throughput Approaches to In Vitro Allergy Diagnosis. Curr Allergy Asthma Rep. 2015;15(7):36. Erratum in: Curr Allergy Asthma Rep. 2015;15(8):52. PMCID: PMC4745341.
Osinski T, Pomés A, Majorek KA, Glesner J, Offermann LR, Vailes LD, Chapman MD, Minor W, Chruszcz M. Structural analysis of Der p 1-antibody complexes and comparison with complexes of proteins or peptides with monoclonal antibodies. J Immunol. 2015;195(1):307-316. PMCID: PMC4475478.
Mueller GA, Pedersen LC, Glesner J, Edwards LL, Zakzuk J, London RE, Arruda LK, Chapman MD, Caraballo L, Pomés A. Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: Relevance for molecular diagnosis. J Allergy Clin Immunol. 2015;136(5):1369-1377. PMCID: PMC4624055.
Wisniewski JA, Commins SP, Agrawal R, Hulse KE, Yu MD, Cronin J, Heymann PW, Pomes A, Platts-Mills TA, Workman L, Woodfolk JA. Analysis of cytokine production by peanut-reactive T cells identifies residual Th2 effectors in highly allergic children who received peanut oral immunotherapy. Clin Exp Allergy. 2015;45(7):1201-13. PMCID: PMC4472497.
Pomés A, Chruszcz M, Gustchina A, Wlodawer A. Interfaces between allergen structure and diagnosis: know your epitopes. Curr Allergy Asthma Rep. 2015;15(8):506. PMCID: PMC4727750.
Koid AE, Chapman MD, Hamilton RG, van Ree R, Versteeg SA, Dreskin SC, Koppelman SJ, Wünschmann S.
Ara h 6 complements Ara h 2 as an important marker for IgE reactivity to peanut. J Agric Food Chem. 2014;62(1):206-213. PMCID: PMC4055559.
Romeo MJ, Agrawal R, Pomés A, Woodfolk JA. J Allergy Clin Immunol. 2014;134(3):762-3. PMCID: PMC4547453.
Radauer C, Nandy A, Ferreira F, Goodman RE, Larsen JN, Lidholm J, Pomés A, Raulf-Heimsoth M, Rozynek P, Thomas WR, Breiteneder H. Update of the WHO/IUIS Allergen Nomenclature Database based on analysis of allergen sequences. Allergy. 2014;69(4):413-9.
