MARIA®—the Multiplex Array for Indoor Allergens—combines InBio’s innovative panels of monoclonal antibodies with the Luminex xMAP® multiplexing technology. MARIA technology uses Luminex MagPlex® magnetic polystyrene microspheres internally dyed with distinct fluorophores to create up to 80 distinctly coded bead sets. Capture antibodies are covalently coupled to different bead sets and then used to develop quantitative immunoassays using biotinylated detector antibodies and a reporting fluorophore.
A wide range of environmental allergens.
WIth MARIA, up to 17 common environmental allergens can currently be measured simultaneously. The detection panel is continuously being enlarged to include other allergens.
- Dust mite (Der p 1, Der f 1, Der p 2, Der p 23, and Blo t 5)
- Cat (Fel d 1)
- Dog (Can f 1)
- Mouse (Mus m 1)
- Rat (Rat n 1)
- Cockroach (Bla g 2)
- Molds Alternaria (Alt a 1) and Aspergillus (Asp f 1)
- Cannabis (Can s 3),
- Pollen allergens of birch (Bet v 1), ragweed, (Amb a 1), timothy grass (Phl p 5), and ryegrass (Lol p 1)
MARIA® for Food covers many major allergens.
InBio has developed panels to detect up to 17 major food allergens, including:
- Peanut (Ara h 1, Ara h 3, Ara h 6)
- Egg (Gal d 1, Gal d 2)
- Milk (Bos d 5, Bos d 11)
- Shrimp (Tropomyosin)
- Cashew (Ana o 3)
- Hazelnut (Cor a 9)
- Almond (Pru du 6)
- Walnut (Jug r 1)
- Soy (Gly m 5)
- Celery (Api g 1)
- Mustard (Sin a 1)
- Carp Fish (Cyp c 1)
- Sesame (Ses i)
Technical support and details on MARIA®.
Get additional information on MARIA®, including a comparison with traditional ELISA methods.
InBio can also provide assistance and training in setting up laboratories for ELISA or MARIA®. Almost all the commercial allergen testing laboratories in the U.S. (and elsewhere) use our assays, and most have been trained by InBio staff via our customized training program.
