Endotoxins originating from gram-negative bacterial cell walls are known to cause adverse health effects. Airborne endotoxin exposure in both industrial and workplace environments is associated with respiratory conditions. Moreover, biological samples for injection must be analyzed for endotoxin content and fall below a pre-defined limit set by health and safety bodies worldwide.

InBio offers the latest endotoxin testing for analyzing environmental, biological, and medical device samples. As well as the traditional LAL assay, InBio now offers endotoxin testing using the Recombinant Factor C (rFC) method. Advantages of the rFC assay include endotoxin specificity, sustainability, lot-to-lot consistency, increased precision.

InBio also offers the USP and FDA approved gel clot method: a qualitative alternative that has a defined EU/mL cutoff to determine a positive/negative result. The gel clot test provides a more economical option if exact endotoxin concentration is not needed, but rather if the concentration is above or below a specific concentration.

InBio provides analysis service for multiple enzymes across various sample types, including air filters and surface wipes, liquid samples, and product samples to assist organizations in occupational health and safety monitoring.

Enzymes are being increasingly used in the food and cleaning product industry. Occupational exposure should be monitored. Enzymes are known sensitizers for respiratory allergy, with subtilisin (protease) being the most common sensitizer. Occupational exposure limits typically range from 15-60 ng/m3. Let InBio assist with your product and occupational health and safety monitoring.

In addition to InBio’s standard enzyme analysis service, we can support safety research by running exposure studies in our UK state-of-the-art Environmental Testing Suite. The ETS is built to AHAM specifications and is designed to assess potential exposure risks and effectiveness of cleaning procedures.

It is estimated that 10-25% of allergic occupational asthma and rhinitis are caused by foods. Sensitization and occupational asthma to food and agricultural allergens is a growing concern for soy, fish and shellfish processing plant workers. Monitoring allergen exposure can assist employers in their duties of safeguarding employees, when performing risk assessments and preventative and corrective actions.

InBio offers highly specific and sensitive immunoassays, including MARIA® for Foods and analysis services for the detection of Soy (Gly m 5), Shellfish (Shrimp) Tropomyosin and fish parvalbumin (Cyp c 1). These analysis methods can be utilized for the measurement of airborne allergens from air filters and other sample types. Current literature suggests 0.1 ug/m3 of soy allergen as an occupational exposure limit.

MARIA® for Foods provides another high-quality tool for IAQ investigations of food allergens in the environment, including managing food allergens in schools, early care centers, hospitals, and public institutions, improving allergen risk assessments and developing thresholds based on well-defined allergen doses and exposures. Most importantly, integration of MARIA® for Foods into IAQ practices should reduce the risks of accidental exposure for food allergic individuals.

Whether you conduct primary research on allergens, develop diagnostic systems, or create products to alleviate environmental and food allergies, you need expertise in action. And that’s exactly what InBio delivers, across everything from highly purified allergens and advanced test kits, to environmental and food allergen testing, to contract research for specialized needs.

• Broad product catalog
• Deep scientific background
  
• Ongoing commitment to R&D
  
• Well-documented subject-matter expertise
  
• Direct contact with our scientific team
  
• Flexible, collaborative relationships