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Gene Editing of the Major Cat Allergen, Fel d 1

Indoor Biotechnologies is applying CRISPR gene editing to delete Fel d 1 from cat cells, an approach to creating a hypoallergenic cat. Join Indoor Biotechnologies scientists to discuss details of the CRISPR Cat project on the holiday edition of our webinar series on Wednesday, December 8th at 11am EST.

Indoor Biotechnologies scientists are investigating the role of Fel d 1 across all cats, both domesticated and wild. Fel d 1 is the cat allergen of choice as it accounts for 60-90% of anti-cat IgE. Significant research has been conducted at Indoor Biotechnologies to identify conserved regions of the Fel d 1 genes and to delete Fel d 1 from feline cells using CRISPR as an approach that could ultimately be used to generate Fel d 1-free cats.
The webinar will cover CRISPR Cat in detail, providing the origins, technical background, data, and future goals of the project.

Learning Objectives:
  • Learn more on the history of CRISPR Cat, including how the gene for Fel d 1 was first isolated.
  • Learn more about CRISPR Cat milestones to date, including the development, methods, and results.
  • Understand the importance of CRISPR Cat, and how the project may have larger implications on the application of CRISPR technology in allergy.