The Multiplex Array for Indoor Allergens (MARIA®) combines Indoor Biotechnologies proprietary panels of monoclonal antibodies with the Luminex xMAP® multiplexing technology. MARIA® technology uses polystyrene microspheres that are internally dyed with distinct fluorophores to create as many as 100 distinctly coded bead sets. Capture antibodies are covalently coupled to different bead sets and then used to develop quantitative immunoassays using biotinylated detector antibodies and a reporting fluorophore.
Up to 11 common allergens of dust mite (Der p 1, Der f 1 and Mite Group 2), cat (Fel d 1), dog (Can f 1), mouse (Mus m 1), rat (Rat n 1), cockroach (Bla g 2), Alternaria (Alt a 1) and the pollen allergens of birch (Bet v 1) and timothy grass (Phl p 5) can currently be measured simultaneously using this technology. The detection panel is continuously being enlarged to include other allergens, such as food allergens and other molds.
Check the Value Proposition for ELISA and MARIA®, which outlines the pros and cons of each assay, and our Technical Information on MARIA®. Whatever the choice, Indoor Biotechnologies can provide assistance and training in setting up laboratories for ELISA or MARIA®. Almost all the commercial allergen testing laboratories in the U.S. (and elsewhere) use our assays. Most of these labs have been trained by Indoor Biotechnologies professional staff on our annual training course or have received customized training through our company.
Indoor Biotechnologies provides comprehensive allergen testing services worldwide. We partner with companies from the indoor air quality, occupational health and industrial hygiene industry to expand the provision of allergen exposure assessments. This helps companies become part of the solution and to address environmental exposures in the home and the workplace that have known health effects.
Indoor Biotechnologies can help:
MARIA® sub-distributors are authorized through a business development agreement to use MARIA® kits and to carry out MARIA® testing on a fee-for-service basis. MARIA® Sub-Distributors provide comparable quality MARIA® services to Indoor Biotechnologies and are able to integrate MARIA® services into their businesses to generate additional income streams and revenues. MARIA® Sub-Distributor benefits are similar to those provided to Service Partners. They also include discounts on MARIA® kits as well as sharing of technical information, know how and intellectual property on MARIA®.
To see the distributor in your area, move your mouse over the icons on the map.