Natural Der f 1 (NA-DF1-1)

Natural Der f 1 (NA-DF1-1)
Product Code: NA-DF1-1
Availability: In Stock
Price: $545.00
Qty:  
Allergen: nDer f 1 (Dermatophagoides farinae allergen 1)
Unit: 250µg
Source: D. farinae culture medium
Mol. Wt: 24kD
Purification:

From mite culture by affinity chromatography. Purity on
silver stained SDS-PAGE >95%.

Concentration:

See package insert. 

Formulation:

Preservative-free and carrier-free in phosphate buffered saline,
pH 7.4. Sterile filtered.

Storage: Store at -20ºC
Notes: (1) Not tested for endotoxin
PDB: 3D6S X-ray crystal structure
Product Resources: Natural Der f 1 Certificate of Analysis
Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use.
References:  
  1. Lombardero M,  Heymann PW,  Platts-Mills TAE,  Fox JW, Chapman MD.  Conformational stability of B cell epitopes on Group I and Group II Dermatophagoides spp. allergens.  Effect of thermal and chemical denaturation on the binding of murine IgG and human IgE antibodies.  J Immunol 1990; 144:1353-1360.
  2. Chruszcz M, Chapman MD, Vailes LD, Stura EA, Saint-Remy JM, Minor W, Pomés A. Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface- exposed residues that may influence antibody binding. J Mol Biol. 2009; 386:520-530.
  3. Chruszcz M, Pomés A, Glesner J, Vailes LD, Osinski T, Porebski PJ, Majorek KA, Heymann PW, Platts-Mills TAE, Minor W, Chapman MD. Molecular determinants for antibody binding on Group 1 house dust mite allergens. J Biol Chem 2012; 287:7388-7398.
 
File Name Size Added Link
NA-DF1_CoA 33.56KB 20/05/2014 Download
Natural Der f 1 Certificate of Analysis
    54.221.29.4
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