Purified Flagellin from Bacillus subtilis (NB-FLA-1)

Purified Flagellin from Bacillus subtilis (NB-FLA-1)
Product Code: NB-FLA-1
Availability: In Stock
Price: $295.00

Flagellin, Microbial Exposure and Allergic Responses

Exposure to microbial products can influence the development of IgE responses.

Bacillus image

Recent studies by Cook and colleagues at NIEHS suggest that exposure to bacterial flagellin, which binds to toll-like receptor 5, can prime allergic responses to indoor allergens (see reference).

As part of a new initiative in innate immunity, Indoor Biotechnologies offers bacterial flagellin as a new product line. Indoor Biotechnologies has an SBIR Phase I grant to develop a high throughput immunoassay to measure environmental exposure to flagellin. As part of these studies, we have a new product - purified flagellin (~90% purity) from Bacillus subtilis.

Allergen: Purified flagellin
Unit: 50µg
Source: Bacillus subtilis

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Concentration: Please inquire

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Storage: Store at -20ºC
Notes: Purifty verified by mass spectrometry and monoclonal antibody binding
Product Resources: Please inquire
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For Research Use Only: Not for Diagnostic or Therapeutic Use

Wilson RH, Maruoka S, Whitehead GS, Foley JF, Flake GP, Sever ML, Zeldin DC, Kraft M, Garantziotis S, Nakano H, Cook DN. The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens. Nat Med. 2012 Nov;18(11):1705-10. doi: 10.1038/nm.2920. Epub 2012 Oct 14. PubMed PMID: 23064463; PubMed Central PMCID: PMC3493750.


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