Biotin Natural Ara h 2 (BI-NAH2-4)

Biotin Natural Ara h 2 (BI-NAH2-4)
Product Code: BI-NAH2-4
Availability: 10 Business Day Lead Time
Price: $2,600.00
Qty:  
Allergen: Biotinylated nAra h 2 (Arachis hypogaea allergen 2)
Unit: 1mg
Source: Light roasted peanut flour (Runner cultivar)   
Mol. Wt: 17-19 kD doublet
Purification:

From delipidated peanut extract by multi-step chromatography. Purity on silver stained SDS-PAGE >95%.

Concentration: See product insert. By Advanced Protein Assay (Cytoskeleton Inc., Denver, CO)
Formulation:

Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Sterile filtered.

Storage: Store at -20ºC
Notes:

 

(1) Ara h 2 appears as a doublet (4).

(2) Protect from exposure to light.

(3) Avoid repeated freeze-thaw cycles.

 

PDB:  
Product Resources: Biotin Natural Ara h 2 Certificate of Analysis
Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use.
References:  

Burks AW, Williams LW, Connaughton C, Cockrell G, O’Brien TJ, Helm RM. Identification and characterization of a second major peanut allergen, Ara h II, with use of the sera of patients with atopic dermatitis and positive peanut challenge. J Allergy Clin Immunol 1992;90:962-9.

Sen M, Kopper R, Pons L, Abraham EC, Burks W, Bannon GA. Protein structure plays a critical role in peanut allergen stability and may determine immunodominant IgE-Binding epitopes. J Immunol 2002;169:882-7.

Flinterman AE, van Hoofen E, den Hartog Jager CF, Koppelman S, Pasmans SG, Hoekstra MO, Bruijnzeel-Koomen CA, Knulst AC, Knol EF. Children with peanut allergy recognize predominantly Ara h2 and Ara h 6, which remains stable over time. Clin Exp Allergy 2007;37:1221-8..

McDermott RA, Porterfield HS, El Mezayen R, Burks AW, Pons L, Schlichting DG, Solomon B, Redzic, JS, Harbeck RJ, Duncan MW, Hansen KC, Dreskin SC. Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation. Clin Exp Allergy 2007;37:752-763.

 
File Name Size Added Link
BI-AH2_CoA 38.38KB 20/05/2014 Download
Biotin Natural Ara h 2 Certificate of Analysis
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